The harley street vascular

Iliac vein stenting for chronic venous insufficiency and leg ulcers

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The harley street vascular

What Is Chronic Venous Insufficiency?

Chronic Venous Insufficiency (CVI) is a condition characterised by poor venous return from the legs to the heart, leading to increased pressure in the veins of the lower limbs.

This venous hypertension can result from valvular incompetence, obstruction, or a combination of both, causing blood to pool in the legs.

What Are Leg Ulcers?

Venous leg ulcers are some of the most severe complications associated with CVI. They are open sores or wounds when skin breaks down, revealing the underlying flesh.

Venous ulcers are typically located near the ankle and may be slow to heal. These ulcers arise from prolonged venous hypertension that damages the skin and surrounding tissues. If infected, they can also be painful and foul smelling.

Anatomy and Pathophysiology

Understanding the Venous System

The lower limbs contain a network of veins, which includes superficial veins (close to the skin’s surface), deep veins (located deeper within the leg), and perforating veins (which connect the superficial and deep veins).

Deep veins send blood back to the heart, and the iliac veins are major deep veins that carry blood from the legs to the heart. However, these veins can become blocked or compressed, leading to circulation problems.

Causes of CVI

  • Valve failure: When valves do not work properly, blood can flow backwards (reflux) and pool in the legs, causing increased pressure.
  • Venous obstruction: Something blocks the vein, hindering blood flow and increasing leg pressure. This can be due to blood clots or external pressure on a vein.
How CVI Leads to Leg Ulcers?

The continuous high pressure in the veins from CVI causes inflammation and damages skin and tissues, eventually leading to ulcers, especially near the ankles.

Iliac Vein Stenting

Iliac vein stenting is a medical procedure designed to alleviate symptoms of CVI by treating obstructions in the iliac vein. It is usually performed for severe symptoms that do not respond to medical treatment and compression therapy, or to prevent a recurrent DVT (Deep Vein Thrombosis) in patients who have already had thrombosis (clotting) of the iliac vein previously.

The procedure involves placing a stent, which is a small mesh tube, inside the iliac vein. The stent acts to keep the vein open, preventing it from narrowing or being compressed, which ensures normal blood flow from the legs back to the heart.

Diagnosis

Diagnosing CVI and deciding on iliac vein stenting involves several steps.

Medical History and Symptoms

The first step is to talk about symptoms that may suggest CVI, such as leg swelling, pain, recurrent varicose veins, and skin changes. History of DVT or leg injuries is carefully reviewed.

Physical Examination

The physical examination focuses on the legs, looking for signs of CVI. The surgeon may also check how well the leg veins are functioning.

Diagnostic Tests

  • Doppler Ultrasound
    This non-invasive test uses sound waves to visualise blood flow and check for vein valve function and obstruction.
  • CT or MRI Venography
    These are done to identify the anatomy of the involved veins and the extent of the disease. They also help to ensure that other causes of vein compression like tumours which may need treatment are ruled out.
  • Echocardiogram
    Patients who have had a previous DVT and pulmonary embolism (PE) are assessed to see if the clots in the lungs have affected their heart function from high pressure in the pulmonary arteries.
  • Thrombophilia screen
    These are blood tests done to rule out inherited or acquired predisposition to clotting, which may affect the duration and type of the blood thinners used after iliac vein stenting.
  • Venography
    An imaging test where a contrast dye is injected into the veins, providing detailed images of the veins’ structure and revealing blockages. This is usually done along with IVUS as part of the stenting procedure itself, although is sometimes performed as a diagnostic test as well.
  • Intravascular Ultrasound (IVUS)
    A minimally invasive test that offers a detailed view of the vein from inside, identifying narrowing or blockages not easily seen on other imaging tests.

Overview of the Procedure

Accessing the Vein

The stenting procedure usually starts with the surgeon making a small incision under ultrasound guidance to access a vein in the leg or neck. Usually the leg on both sides is accessed to ensure a full evaluation of the veins being treated.

Guiding the Catheter

A catheter (a thin, flexible tube) is then guided to the site of the obstruction in the iliac vein, using X-ray imaging.

Placing the Stent

Once the obstruction is reached, it is first treated with a balloon angioplasty to expand the vein to its normal size. Intra vascular ultrasound is used to guide the size of stent required and the best position for it to be placed. A suitable sized stent is then deployed into the expanded vein. This stent expands, opening up the blocked section of the vein to restore normal blood flow.

Finishing the Procedure

After the stent is in place, the catheter is removed, and the incision is closed. The entire process typically takes 1-2 hours, depending on the complexity.

Post-Procedure Care

Immediate Post-Procedure Care

  • Monitoring: Patients are usually monitored for a few hours after the procedure to ensure no immediate complications, such as bleeding from the catheter insertion site.
  • Activity: Most patients can walk shortly after the procedure and are encouraged to do so to promote blood flow.

Medication

  • Blood Thinners: Anticoagulants are usually prescribed to prevent blood clot formation within the stent or the treated vein for a period of time.
  • Pain Management: Over-the-counter or prescription pain relievers may be recommended to manage any discomfort following the procedure.

Follow-Up Care

  • Follow-Up Visits: Regular follow-up appointments are needed to monitor the stent’s patency and the overall health of the venous system. These visits may include physical exams and imaging tests, such as ultrasound, and sometimes CT venogram scans.
  • Compression Therapy: Continued use of compression stockings may be advised to support vein health and prevent swelling.
  • Post-procedure ulcer care: If an ulcer was present initially, continued specialist care of the wound is required till it heals.

Risks and Complications

Like any medical procedure, iliac vein stenting carries certain risks and potential complications.

Bleeding

The catheter insertion site may bleed, though this is usually minor and controlled quickly. Bleeding or bruising can also occur from the blood thinners prescribed after vein stenting, and your doctor will advise you on how to manage this if it occurs.

Infection

There’s a small risk of infection at the catheter insertion site or within the treated vein.

Stent Migration

Rarely, the stent may move from its original placement site. This risk is minimised using dedicated vein stents specifically designed to be placed in veins and not arteries (which are very different) and also well-suited to the patient’s vein size.

Stent Thrombosis

Blood clots can form within the stent, potentially blocking blood flow. These may require further procedures to re-establish the flow.

Vein Perforation

There’s a slight chance of damaging the vein during the procedure. However, such occurrences are infrequent and usually have minimal long-term consequences.

Post-Thrombotic Syndrome

Even after successful stenting, some patients may experience ongoing symptoms like swelling and pain, known as post-thrombotic syndrome.

Frequently Asked Questions

Will I need to stay in the hospital overnight after the procedure?

Most patients are discharged the same day or the next morning after iliac vein stenting, as it’s minimally invasive and recovery times are relatively quick.

Is iliac vein stenting painful?

Patients are given local anaesthesia at the insertion site, minimising pain during the procedure. Post-procedure discomfort is usually mild and manageable with over-the-counter pain relief. Some patients, especially if very slim, can have back pain after the stent for a few days after stenting as the stent continues to expand a little even after the procedure is completed. This is usually managed easily with simple analgesia.

What happens if the stent becomes blocked or moves?

If stent blockage or migration occurs, symptoms may return, and further intervention might be needed. Regular follow-up imaging helps in the early detection of such issues, allowing for timely management.

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